For I/O-intensive workloads that have multiple vNUMA nodes, the NUMA assignment for storage controllers can be adjusted. A physical PCIe device usually has a home pNUMA node. The vNUMA assignment of each I/O device can be adjusted via a Windows Server registry setting, starting with Windows Server 2012. For the larger I/O-intensive workloads, the workload distribution can benefit from distributing the I/O controllers across the available vNUMA nodes. For more information, see the Learn topic “Hyper-V Storage I/O Performance” .